The Fumarprotocetraric Acid Inhibits Tau Covalently, Avoiding Cytotoxicity of Aggregates in Cells

The Fumarprotocetraric Acid Inhibits Tau Covalently, Avoiding Cytotoxicity of Aggregates in Cells

Neurodegenerative disorders, including Tauopathies that involve tau protein, base their pathological mechanism on forming proteinaceous aggregates, which has a deleterious effect on cells triggering an inflammatory response. Moreover, tau inhibitors can exert their mechanism of action through noncov...

Full description

Bibliographic Details
Main Authors: Camila González, Constanza Cartagena, Leonardo Caballero, Francisco Melo, Carlos Areche, Alberto Cornejo
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Molecules
Subjects:
lichens
tauopathies
α,β carbonyl group
inhibitors
aggregates
cytotoxicity
Online Access:https://www.mdpi.com/1420-3049/26/12/3760

Internet

https://www.mdpi.com/1420-3049/26/12/3760

Similar Items