Assessment of aberrant DNA methylation two years after paediatric critical illness: a pre-planned secondary analysis of the international PEPaNIC trial

Assessment of aberrant DNA methylation two years after paediatric critical illness: a pre-planned secondary analysis of the international PEPaNIC trial

Critically ill children requiring intensive care suffer from impaired physical/neurocognitive development 2 y later, partially preventable by omitting early use of parenteral nutrition (early-PN) in the paediatric intensive-care-unit (PICU). Altered methylation of DNA from peripheral blood during PI...

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Bibliographic Details
Main Authors: Grégoire Coppens, Ilse Vanhorebeek, Ines Verlinden, Inge Derese, Pieter J Wouters, Koen F. Joosten, Sascha C. Verbruggen, Fabian Güiza, Greet Van den Berghe
Format: Article
Language:English
Published: Taylor & Francis Group 2023-12-01
Series:Epigenetics
Subjects:
critical illness
children
picu
dna methylation
epigenetic
neurocognitive development
growth
development
nutrition
parenteral nutrition
Online Access:http://dx.doi.org/10.1080/15592294.2022.2146966

Internet

http://dx.doi.org/10.1080/15592294.2022.2146966

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