The contribution of tumor necrosis factor to multiple sclerosis: a possible role in progression independent of relapse?

The contribution of tumor necrosis factor to multiple sclerosis: a possible role in progression independent of relapse?

Abstract Tumor necrosis factor (TNF) is a pleiotropic cytokine regulating many physiological and pathological immune-mediated processes. Specifically, it has been recognized as an essential pro-inflammatory cytokine implicated in multiple sclerosis (MS) pathogenesis and progression. MS is a chronic...

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Bibliographic Details
Main Authors: Valentina Mazziotti, Francesco Crescenzo, Ermanna Turano, Maddalena Guandalini, Maddalena Bertolazzo, Stefano Ziccardi, Federica Virla, Valentina Camera, Damiano Marastoni, Agnese Tamanti, Massimiliano Calabrese
Format: Article
Language:English
Published: BMC 2024-08-01
Series:Journal of Neuroinflammation
Subjects:
TNF biology
MS pathology
PIRA
MS lesions
Chronic compartmentalized inflammation
Neurodegeneration
Online Access:https://doi.org/10.1186/s12974-024-03193-6

Internet

https://doi.org/10.1186/s12974-024-03193-6

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