R-spondin3 is a myokine that differentiates myoblasts to type I fibres
Abstract Muscle fibres are broadly categorised into types I and II; the fibre-type ratio determines the contractile and metabolic properties of skeletal muscle tissue. The maintenance of type I fibres is essential for the prevention of obesity and the treatment of muscle atrophy caused by type 2 dia...
Main Authors: | Yoshitaka Mita, Haonan Zhu, Yasuro Furuichi, Hiroki Hamaguchi, Yasuko Manabe, Nobuharu L. Fujii |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2022-07-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-022-16640-2 |
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