Nodal promotes colorectal cancer survival and metastasis through regulating SCD1-mediated ferroptosis resistance
Abstract Re-expression of an embryonic morphogen, Nodal, has been seen in several types of malignant tumours. By far, studies about Nodal’s role in colorectal cancer (CRC) remain limited. Ferroptosis is essential for CRC progression, which is caused by cellular redox imbalance and characterized by l...
Main Authors: | , , , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2023-03-01
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Series: | Cell Death and Disease |
Online Access: | https://doi.org/10.1038/s41419-023-05756-6 |