A splice site variant in the bovine RNF11 gene compromises growth and regulation of the inflammatory response.

A splice site variant in the bovine RNF11 gene compromises growth and regulation of the inflammatory response.

We report association mapping of a locus on bovine chromosome 3 that underlies a Mendelian form of stunted growth in Belgian Blue Cattle (BBC). By resequencing positional candidates, we identify the causative c124-2A>G splice variant in intron 1 of the RNF11 gene, for which all affected animals a...

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Bibliographic Details
Main Authors: Arnaud Sartelet, Tom Druet, Charles Michaux, Corinne Fasquelle, Sarah Géron, Nico Tamma, Zhiyan Zhang, Wouter Coppieters, Michel Georges, Carole Charlier
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3305398?pdf=render

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http://europepmc.org/articles/PMC3305398?pdf=render

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