Tetrandrine Prevents Neomycin-Induced Ototoxicity by Promoting Steroid Biosynthesis

Tetrandrine Prevents Neomycin-Induced Ototoxicity by Promoting Steroid Biosynthesis

Aminoglycoside antibiotics are widely used for the treatment of serious acute infections, life-threatening sepsis, and tuberculosis, but all aminoglycosides cause side effects, especially irreversible ototoxicity. The mechanisms underlying the ototoxicity of aminoglycosides need further investigatio...

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Bibliographic Details
Main Authors: Qilei Zhang, Yunhao Wu, Yan Yu, Yuguang Niu, Qiaojun Fang, Xin Chen, Jieyu Qi, Chen Zhang, Geping Wu, Kaiming Su, Renjie Chai
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-04-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
tetrandrine
hair cell
apoptosis
oxidative stress
steroid biosynthesis
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2022.876237/full

Internet

https://www.frontiersin.org/articles/10.3389/fbioe.2022.876237/full

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