The Transcription Factor TCF1 in T Cell Differentiation and Aging

The transcription factor T cell factor 1 (TCF1), a pioneer transcription factor as well as a downstream effector of WNT/β-catenin signaling, is indispensable for T cell development in the thymus. Recent studies have highlighted the additional critical role of TCF1 in peripheral T cell responses to a...

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Bibliographic Details
Main Authors: Chulwoo Kim, Jun Jin, Cornelia M. Weyand, Jörg J. Goronzy
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/21/18/6497