Correlates of vaccine protection against Mycobacterium avium sub-species paratuberculosis infection revealed in a transcriptomic study of responses in Gudair® vaccinated sheep

A critical hindrance in the development of effective vaccine strategies to combat infectious disease is lack of knowledge about correlates of protection and of the host responses necessary for successful adaptive immunity. Often vaccine formulations are developed by stepwise experimentation, with in...

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Bibliographic Details
Main Authors: Auriol C. Purdie, Karren M. Plain, Hannah Pooley, Douglas J. Begg, Kumudika de Silva, Richard J. Whittington
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Veterinary Science
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fvets.2022.1004237/full