Tissue plasminogen activator with prolonged dwell time effectively evacuates pleural effusions

Tissue plasminogen activator with prolonged dwell time effectively evacuates pleural effusions

Abstract Objectives Fibrinolytic therapy can be effective for management of complex pleural effusions. Tissue plasminogen activator (tPA, 10 mg) and deoxyribonuclease (DNAse) every 12 h with a dwell time of one hour is a common strategy based on published data. We used a simpler protocol of tPA (4 m...

Full description

Bibliographic Details
Main Authors: Alexandra Townsend, Harsha Raju, Krystina A. Serpa, Rachel Pruett, Syed S. Razi, Francisco A. Tarrazzi, Catherine M. Tami, Mark I. Block
Format: Article
Language:English
Published: BMC 2022-12-01
Series:BMC Pulmonary Medicine
Subjects:
Parapneumonic effusion
Empyema
tPA
Fibrinolytic therapy
Online Access:https://doi.org/10.1186/s12890-022-02261-y

Internet

https://doi.org/10.1186/s12890-022-02261-y

Similar Items