IL-27 imparts immunoregulatory function to human NK cell subsets.

Interleukin-27 (IL-27) is a cytokine with multiple roles in regulating the immune response, but its effect on human CD56(bright) and CD56(dim) NK cell subsets is unknown. NK cell subsets interact with other components of the immune system, leading to cytotoxicity or immunoregulation depending on sti...

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Bibliographic Details
Main Authors: Alice Laroni, Roopali Gandhi, Vanessa Beynon, Howard L Weiner
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3198386?pdf=render