A novel Modulator of Ring Stage Translation (MRST) gene alters artemisinin sensitivity in Plasmodium falciparum

A novel Modulator of Ring Stage Translation (MRST) gene alters artemisinin sensitivity in Plasmodium falciparum

ABSTRACT The implementation of artemisinin (ART) combination therapies (ACTs) has greatly decreased deaths caused by Plasmodium falciparum malaria, but increasing ACT resistance in Southeast Asia and Africa could reverse this progress. Parasite population genetic studies have identified numerous gen...

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Bibliographic Details
Main Authors: Caroline Simmons, Justin Gibbons, Chengqi Wang, Camilla Valente Pires, Min Zhang, Faiza Siddiqui, Jenna Oberstaller, Debora Casandra, Andreas Seyfang, Liwang Cui, Thomas D. Otto, John H. Adams
Format: Article
Language:English
Published: American Society for Microbiology 2023-08-01
Series:mSphere
Subjects:
malaria
antimalarial agents
drug resistance mechanisms
gene annotation
Online Access:https://journals.asm.org/doi/10.1128/msphere.00152-23

Internet

https://journals.asm.org/doi/10.1128/msphere.00152-23

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