Bring along your friends: Homotypic and heterotypic circulating tumor cell clustering to accelerate metastasis

Metastasis formation is a hallmark of invasive cancers and it is achieved through the shedding of circulating tumor cells (CTCs) from the primary site into the blood circulation. There, CTCs are found as single cells or as multicellular clusters, with clusters carrying an elevated ability to survive...

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Bibliographic Details
Main Author: Nicola Aceto
Format: Article
Language:English
Published: Elsevier 2020-02-01
Series:Biomedical Journal
Online Access:http://www.sciencedirect.com/science/article/pii/S2319417019305086