Adoptive T cell therapy cures mice from active hemophagocytic lymphohistiocytosis (HLH)

Adoptive T cell therapy cures mice from active hemophagocytic lymphohistiocytosis (HLH)

Abstract Primary hemophagocytic lymphohistiocytosis (HLH) is a hyperinflammatory syndrome caused by impaired lymphocyte cytotoxicity. First‐line therapeutic regimens directed against activated immune cells or secreted cytokines show limited efficacy since they do not target the underlying immunologi...

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Bibliographic Details
Main Authors: Kristoffer Weißert, Sandra Ammann, Tamara Kögl, Viviane Dettmer‐Monaco, Christoph Schell, Toni Cathomen, Stephan Ehl, Peter Aichele
Format: Article
Language:English
Published: Springer Nature 2022-12-01
Series:EMBO Molecular Medicine
Subjects:
adoptive T cell therapy
hemophagocytic lymphohistiocytosis
hyperinflammation
virus‐specific T cells
Online Access:https://doi.org/10.15252/emmm.202216085

Internet

https://doi.org/10.15252/emmm.202216085

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