Offspring's leukocyte telomere length, paternal age, and telomere elongation in sperm.

Leukocyte telomere length (LTL) is a complex genetic trait. It shortens with age and is associated with a host of aging-related disorders. Recent studies have observed that offspring of older fathers have longer LTLs. We explored the relation between paternal age and offspring's LTLs in 4 diffe...

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Main Authors: Masayuki Kimura, Lynn F Cherkas, Bernet S Kato, Serkalem Demissie, Jacob B Hjelmborg, Michael Brimacombe, Adrienne Cupples, Janice L Hunkin, Jefferey P Gardner, Xiaobin Lu, Xiaojian Cao, Malinee Sastrasinh, Michael A Province, Steven C Hunt, Kaare Christensen, Daniel Levy, Tim D Spector, Abraham Aviv
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-02-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC2242810?pdf=render