CHANGES IN THE MGMT GENE EXPRESSION IN PATIENTS WITH PRIMARY GLIOBLASTOMA AFTER RELAPSE. INFLUENCE OF CLINICAL CHARACTERISTICS AND MGMT EXPRESSION ON SURVIVAL OF PATIENTS

CHANGES IN THE MGMT GENE EXPRESSION IN PATIENTS WITH PRIMARY GLIOBLASTOMA AFTER RELAPSE. INFLUENCE OF CLINICAL CHARACTERISTICS AND MGMT EXPRESSION ON SURVIVAL OF PATIENTS

Background. Over the past 10–15 years, there has been a clearer understanding of the processes occurring in cells of the primary glioblastoma. However, the change in MGMT gene expression and its role after disease relapse remain understudied. Purpose: to study changes in MGMT gene expression in case...

Full description

Bibliographic Details
Main Authors: M. V. Matsko, S. S. Sklyar, A. Yu. Ulitin, D. E. Matsko, E. N. Imyanitov, A. G. Ievleva, V. I. Ni, N. M. Volkov, A. A. Zrelov, A. O. Baksheeva, D. V. Galkina
Format: Article
Language:Russian
Published: Russian Academy of Sciences, Tomsk National Research Medical Center 2021-06-01
Series:Сибирский онкологический журнал
Subjects:
первичная глиобластома
рецидив глиобластомы
мутации в генах idh1 и idh2
ген mgmt
темозоломид
первый безрецидивный период
степень циторедукции
Online Access:https://www.siboncoj.ru/jour/article/view/1802

Internet

https://www.siboncoj.ru/jour/article/view/1802

Similar Items