Mycobacterium leprae phenolglycolipid-1 expressed by engineered M. bovis BCG modulates early interaction with human phagocytes.

Mycobacterium leprae phenolglycolipid-1 expressed by engineered M. bovis BCG modulates early interaction with human phagocytes.

The species-specific phenolic glycolipid 1 (PGL-1) is suspected to play a critical role in the pathogenesis of leprosy, a chronic disease of the skin and peripheral nerves caused by Mycobacterium leprae. Based on studies using the purified compound, PGL-1 was proposed to mediate the tropism of M. le...

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Bibliographic Details
Main Authors: Guillaume Tabouret, Catherine Astarie-Dequeker, Caroline Demangel, Wladimir Malaga, Patricia Constant, Aurélie Ray, Nadine Honoré, Nana Fatimath Bello, Esther Perez, Mamadou Daffé, Christophe Guilhot
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-10-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC2958813?pdf=render

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http://europepmc.org/articles/PMC2958813?pdf=render

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