Blocking Serum Amyloid-P Component from Binding to Macrophages and Augmenting Fungal Functional Amyloid Increases Macrophage Phagocytosis of <i>Candida albicans</i>

Blocking Serum Amyloid-P Component from Binding to Macrophages and Augmenting Fungal Functional Amyloid Increases Macrophage Phagocytosis of <i>Candida albicans</i>

<i>Candida</i>-macrophage interactions are important immune defense responses associated with disseminated and deep-seated candidiasis in humans. Cells of <i>Candida</i> spp. express functional amyloids on their surfaces during the pathogenesis of disseminated candidiasis. Th...

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Bibliographic Details
Main Authors: Stephen A. Klotz, Nicole Bradley, Peter N. Lipke
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Pathogens
Subjects:
macrophage skewing
pathogen recognition
innate immunity
Online Access:https://www.mdpi.com/2076-0817/11/9/1000

Internet

https://www.mdpi.com/2076-0817/11/9/1000

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