A novel isothermal method for amplification of long specific amplicon from linear template

Abstract Isothermal nucleic acid amplification methods have been successfully developed and applied for diagnostic purpose, especially for detection of pathogens. However, amplicon size of such methods is relatively short (< 500 bp) to limit their application for long amplicon production that can...

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Bibliographic Details
Main Authors: Gun-Soo Park, Jin-Soo Maeng
Format: Article
Language:English
Published: Nature Portfolio 2022-02-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-06785-5