Promises and challenges in pharmacoepigenetics

Pharmacogenetics, the study of how interindividual genetic differences affect drug response, does not explain all observed heritable variance in drug response. Epigenetic mechanisms, such as DNA methylation, and histone acetylation may account for some of the unexplained variances. Epigenetic mechan...

Full description

Bibliographic Details
Main Authors: Delaney A. Smith, Marie C. Sadler, Russ B. Altman
Format: Article
Language:English
Published: Cambridge University Press 2023-01-01
Series:Cambridge Prisms: Precision Medicine
Subjects:
Online Access:https://www.cambridge.org/core/product/identifier/S2752614323000066/type/journal_article