Immune System Dysregulation During Spaceflight: Potential Countermeasures for Deep Space Exploration Missions

Recent studies have established that dysregulation of the human immune system and the reactivation of latent herpesviruses persists for the duration of a 6-month orbital spaceflight. It appears certain aspects of adaptive immunity are dysregulated during flight, yet some aspects of innate immunity a...

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Bibliographic Details
Main Authors: Brian E. Crucian, Alexander Choukèr, Richard J. Simpson, Satish Mehta, Gailen Marshall, Scott M. Smith, Sara R. Zwart, Martina Heer, Sergey Ponomarev, Alexandra Whitmire, Jean P. Frippiat, Grace L. Douglas, Hernan Lorenzi, Judith-Irina Buchheim, George Makedonas, Geoffrey S. Ginsburg, C. Mark Ott, Duane L. Pierson, Stephanie S. Krieger, Natalie Baecker, Clarence Sams
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-06-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.01437/full