Evaluation of roll compaction as a preparation method for hydroxypropyl cellulose-based matrix tablets

Evaluation of roll compaction as a preparation method for hydroxypropyl cellulose-based matrix tablets

Roll compaction was applied for the preparation of hydroxypropyl cellulose (HPC)-based sustained-release matrix tablets. Matrix tablets made via roll compaction exhibited higher dosage uniformity and faster drug release than direct-compacted tablets. HPC viscosity grade, roll pressure, and milling s...

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Bibliographic Details
Main Authors: Imjak Jeon, Tiziana Gilli, Gabriele Betz
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2011-01-01
Series:Journal of Pharmacy and Bioallied Sciences
Subjects:
Dry granulation
hydroxypropyl cellulose
matrix tablet
roll compaction
sustained release
Online Access:http://www.jpbsonline.org/article.asp?issn=0975-7406;year=2011;volume=3;issue=2;spage=213;epage=220;aulast=Jeon

Internet

http://www.jpbsonline.org/article.asp?issn=0975-7406;year=2011;volume=3;issue=2;spage=213;epage=220;aulast=Jeon

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