18 kDa translocator protein positron emission tomography facilitates early and robust tumor detection in the immunocompetent SB28 glioblastoma mouse model

IntroductionThe 18 kDa translocator protein (TSPO) receives growing interest as a biomarker in glioblastoma. Mouse models can serve as an important tool for the investigation of biomarkers in glioblastoma, but several glioblastoma models indicated only low TSPO-PET signals in contrast to high TSPO-P...

Full description

Bibliographic Details
Main Authors: Laura M. Bartos, Sabrina V. Kirchleitner, Jens Blobner, Karin Wind, Lea H. Kunze, Adrien Holzgreve, Lukas Gold, Artem Zatcepin, Zeynep Ilgin Kolabas, Selin Ulukaya, Lorraine Weidner, Stefanie Quach, Denise Messerer, Peter Bartenstein, Joerg C. Tonn, Markus J. Riemenschneider, Sibylle Ziegler, Louisa von Baumgarten, Nathalie L. Albert, Matthias Brendel
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Medicine
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2022.992993/full