Direct and Indirect Inhibition of <italic toggle="yes">Salmonella</italic> Peptide Deformylase by Nitric Oxide

ABSTRACT Salmonella enterica serovar Typhimurium is an intracellular pathogen that elicits nitric oxide (NO·) production by host macrophages. NO· is a potent antimicrobial mediator with diverse targets, including protein thiols and metal centers. The mobilization of zinc from metalloproteins by NO·...

Full description

Bibliographic Details
Main Authors: Anshika Singhal, Ferric C. Fang
Format: Article
Language:English
Published: American Society for Microbiology 2020-12-01
Series:mBio
Subjects:
Online Access:https://journals.asm.org/doi/10.1128/mBio.01383-20