Direct and Indirect Inhibition of <italic toggle="yes">Salmonella</italic> Peptide Deformylase by Nitric Oxide
ABSTRACT Salmonella enterica serovar Typhimurium is an intracellular pathogen that elicits nitric oxide (NO·) production by host macrophages. NO· is a potent antimicrobial mediator with diverse targets, including protein thiols and metal centers. The mobilization of zinc from metalloproteins by NO·...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
American Society for Microbiology
2020-12-01
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Series: | mBio |
Subjects: | |
Online Access: | https://journals.asm.org/doi/10.1128/mBio.01383-20 |