Screening for Anti-HMGCR Antibodies in a Large Single Myositis Center Reveals Infrequent Exposure to Statins and Diversiform Presentation of the Disease

Screening for Anti-HMGCR Antibodies in a Large Single Myositis Center Reveals Infrequent Exposure to Statins and Diversiform Presentation of the Disease

BackgroundThe objective of this study is to assess the frequency of autoantibodies against 3-hydroxy-3-methyl-glutaryl-coenzyme A reductase (HMGCR) in a single center myositis cohort and to analyze associations with statin exposure, clinical features, and outcome of disease course.MethodsA total of...

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Bibliographic Details
Main Authors: Piotr Szczesny, Simone Barsotti, Inger Nennesmo, Olof Danielsson, Maryam Dastmalchi
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-05-01
Series:Frontiers in Immunology
Subjects:
immune-mediated necrotizing myopathy (IMNM)
anti-HMGCR
statin
dermatomyositis
idiopathic inflammatory myopathy
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.866701/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.866701/full

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