Ebola virus protein VP40 stimulates IL-12– and IL-18–dependent activation of human natural killer cells
Accumulation of activated natural killer (NK) cells in tissues during Ebola virus infection contributes to Ebola virus disease (EVD) pathogenesis. Yet, immunization with Ebola virus-like particles (VLPs) comprising glycoprotein and matrix protein VP40 provides rapid, NK cell–mediated protection agai...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
American Society for Clinical investigation
2022-08-01
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| Series: | JCI Insight |
| Subjects: | |
| Online Access: | https://doi.org/10.1172/jci.insight.158902 |