Isocitrate dehydrogenase 2 regulates the proliferation of triple-negative breast cancer through the ferroptosis pathway

Isocitrate dehydrogenase 2 regulates the proliferation of triple-negative breast cancer through the ferroptosis pathway

Abstract Triple-negative breast cancer (TNBC) is currently the type of breast cancer with the worst prognosis; it lacks specific treatments, such as ER/PR antagonistic endocrine and anti-HER2 targeted therapies. Although immunotherapy with immune checkpoints has shown some efficacy in many solid tum...

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Bibliographic Details
Main Authors: Chengwu Zhang, Yuanhong Zhou, Tao Chen, Sudhanshu Bhushan, Shengrong Sun, Panshi Zhang, Yalong Yang
Format: Article
Language:English
Published: Nature Portfolio 2024-02-01
Series:Scientific Reports
Subjects:
Ferroptosis
Triple-negative breast cancer
Proliferation
IDH2
Online Access:https://doi.org/10.1038/s41598-024-55561-0

Internet

https://doi.org/10.1038/s41598-024-55561-0

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