The role of microenvironment in the initiation and evolution of B-cell precursor acute lymphoblastic leukemia

B cell precursor acute lymphoblastic leukemia (BCP-ALL) is a malignant disorder of immature B lineage immune progenitors and is the commonest cancer in children. Despite treatment advances it remains a leading cause of death in childhood and response rates in adults remain poor. A preleukemic state...

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Bibliographic Details
Main Authors: Alicia Garcia-Gimenez, Simon E. Richardson
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-03-01
Series:Frontiers in Oncology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2023.1150612/full