CTL responses of high functional avidity and broad variant cross-reactivity are associated with HIV control.

CTL responses of high functional avidity and broad variant cross-reactivity are associated with HIV control.

Cytotoxic T lymphocyte (CTL) responses targeting specific HIV proteins, in particular Gag, have been associated with relative control of viral replication in vivo. However, Gag-specific CTL can also be detected in individuals who do not control the virus and it remains thus unclear how Gag-specific...

Full description

Bibliographic Details
Main Authors: Beatriz Mothe, Anuska Llano, Javier Ibarrondo, Jennifer Zamarreño, Mattia Schiaulini, Cristina Miranda, Marta Ruiz-Riol, Christoph T Berger, M José Herrero, Eduard Palou, Montse Plana, Morgane Rolland, Ashok Khatri, David Heckerman, Florencia Pereyra, Bruce D Walker, David Weiner, Roger Paredes, Bonaventura Clotet, Barbara K Felber, George N Pavlakis, James I Mullins, Christian Brander
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3251596?pdf=render

Internet

http://europepmc.org/articles/PMC3251596?pdf=render

Similar Items