Gestational hypoxia in late pregnancy differentially programs subcortical brain maturation in male and female rat offspring

Gestational hypoxia in late pregnancy differentially programs subcortical brain maturation in male and female rat offspring

Highlights Brain maturation of the nigrostriatal pathway is sex- and age- dependent. Exposure to hypoxia in late pregnancy impacts brain maturation of the nigrostriatal pathway that can be observed during puberty and young adulthood. Gestational hypoxia impacted female offspring during puberty more...

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Bibliographic Details
Main Authors: E. Nicole Wilson, Steve Mabry, Jessica L. Bradshaw, Jennifer J. Gardner, Nataliya Rybalchenko, Rachel Engelland, Oluwadarasimi Fadeyibi, Oluwatobiloba Osikoya, Spencer C. Cushen, Styliani Goulopoulou, Rebecca L. Cunningham
Format: Article
Language:English
Published: BMC 2022-09-01
Series:Biology of Sex Differences
Subjects:
Prenatal programming
Oxidative stress
Sex differences
Chronic intermittent hypoxia
Ultrasonic vocalizations
Substantia nigra
Online Access:https://doi.org/10.1186/s13293-022-00463-x

Internet

https://doi.org/10.1186/s13293-022-00463-x

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