Mortalin: Protein partners, biological impacts, pathological roles, and therapeutic opportunities

Mortalin: Protein partners, biological impacts, pathological roles, and therapeutic opportunities

Mortalin (GRP75, HSPA9A), a heat shock protein (HSP), regulates a wide range of cellular processes, including cell survival, growth, and metabolism. The regulatory functions of mortalin are mediated through a diverse set of protein partners associated with different cellular compartments, which allo...

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Bibliographic Details
Main Authors: Niki Esfahanian, Cole D. Knoblich, Gaven A. Bowman, Khosrow Rezvani
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-02-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
mortalin (HSPA9)
cancer
protein partners
cellular localization
post-translational modification (PTM)
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2023.1028519/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2023.1028519/full

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