Localized delivery of therapeutics impact laryngeal mechanics, local inflammatory response, and respiratory microbiome following upper airway intubation injury in swine

Localized delivery of therapeutics impact laryngeal mechanics, local inflammatory response, and respiratory microbiome following upper airway intubation injury in swine

Abstract Background Laryngeal injury associated with traumatic or prolonged intubation may lead to voice, swallow, and airway complications. The interplay between inflammation and microbial population shifts induced by intubation may relate to clinical outcomes. The objective of this study was to in...

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Bibliographic Details
Main Authors: Gabriela Gonzales, Ronit Malka, Lisa M. Marinelli, Christine M. Lee, Stacy Cook, Solaleh Miar, Gregory R. Dion, Teja Guda
Format: Article
Language:English
Published: BMC 2024-09-01
Series:Respiratory Research
Subjects:
Laryngeal injury
Endotracheal intubation
Intubation trauma
Airway microbiome
Online Access:https://doi.org/10.1186/s12931-024-02973-1

Internet

https://doi.org/10.1186/s12931-024-02973-1

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