Generation of Cry11 Variants of by Heuristic Computational Modeling

Directed evolution methods mimic in vitro Darwinian evolution, inducing random mutations and selective pressure in genes to obtain proteins with enhanced characteristics. These techniques are developed using trial-and-error testing at an experimental level with a high degree of uncertainty. Therefor...

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Bibliographic Details
Main Authors: Efraín Hernando Pinzón-Reyes, Daniel Alfonso Sierra-Bueno, Miguel Orlando Suarez-Barrera, Nohora Juliana Rueda-Forero, Sebastián Abaunza-Villamizar, Paola Rondón-Villareal
Format: Article
Language:English
Published: SAGE Publishing 2020-07-01
Series:Evolutionary Bioinformatics
Online Access:https://doi.org/10.1177/1176934320924681