Role of genetic variants of autophagy genes in susceptibility for non-medullary thyroid cancer and patients outcome.

Autophagy is a central process in regulation of cell survival, cell death and proliferation and plays an important role in carcinogenesis, including thyroid carcinoma. Genetic variation in autophagy components has been demonstrated to influence the capacity to execute autophagy and is associated wit...

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Bibliographic Details
Main Authors: Theo S Plantinga, Esther van de Vosse, Angelique Huijbers, Mihai G Netea, Leo A B Joosten, Jan W A Smit, Romana T Netea-Maier
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3989221?pdf=render