Biased activity of soluble guanylyl cyclase: the Janus face of thymoquinone

The natural compound thymoquinone, extracted from Nigella sativa (black cumin), is widely used in humans for its anti-oxidative properties. Thymoquinone is known for its acute endothelium-independent vasodilator effects in isolated rat aortae and pulmonary arteries, depending in part on activation o...

Full description

Bibliographic Details
Main Authors: Charlotte Detremmerie, Paul M. Vanhoutte, Susan Leung
Format: Article
Language:English
Published: Elsevier 2017-07-01
Series:Acta Pharmaceutica Sinica B
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211383517302290