Protease activities of vaginal Porphyromonas species disrupt coagulation and extracellular matrix in the cervicovaginal niche
Abstract Porphyromonas asaccharolytica and Porphyromonas uenonis are common inhabitants of the vaginal microbiome, but their presence has been linked to adverse health outcomes for women, including bacterial vaginosis and preterm birth. However, little is known about the pathogenesis mechanisms of t...
Main Authors: | Karen V. Lithgow, Vienna C. H. Buchholz, Emily Ku, Shaelen Konschuh, Ana D’Aubeterre, Laura K. Sycuro |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2022-02-01
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Series: | npj Biofilms and Microbiomes |
Online Access: | https://doi.org/10.1038/s41522-022-00270-7 |
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