Osteocytes/Osteoblasts Produce SAA3 to Regulate Hepatic Metabolism of Cholesterol

Osteocytes/Osteoblasts Produce SAA3 to Regulate Hepatic Metabolism of Cholesterol

Abstract Hypercholesterolaemia is a systemic metabolic disease, but the role of organs other than liver in cholesterol metabolism is unappreciated. The phenotypic characterization of the Tsc1Dmp1 mice reveal that genetic depletion of tuberous sclerosis complex 1 (TSC1) in osteocytes/osteoblasts (Dmp...

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Bibliographic Details
Main Authors: Shijiang Huang, Yuanjun Jiang, Jing Li, Linlin Mao, Zeyou Qiu, Sheng Zhang, Yuhui Jiang, Yong Liu, Wen Liu, Zhi Xiong, Wuju Zhang, Xiaolin Liu, Yue Zhang, Xiaochun Bai, Bin Guo
Format: Article
Language:English
Published: Wiley 2024-06-01
Series:Advanced Science
Subjects:
bone‐liver crosstalk
CYP7A1
hypercholesterolaemia
osteocytes/osteoblasts
SAA3
Online Access:https://doi.org/10.1002/advs.202307818

Internet

https://doi.org/10.1002/advs.202307818

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