Transmembrane amyloid-related proteins in CSF as potential biomarkers for Alzheimer’s disease

Transmembrane amyloid-related proteins in CSF as potential biomarkers for Alzheimer’s disease

In the continuing search for new cerebrospinal fluid (CSF) biomarkers for Alzheimer’s disease (AD), reasonable candidates are the secretase enzymes involved in the processing of the amyloid precursor protein (APP), as well as the large proteolytic cleavage fragments sAPPα and sAPPβ. The enzymatic ac...

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Bibliographic Details
Main Authors: Inmaculada eLopez-Font, Inmaculada eCuchillo-Ibañez, Aitana eSogorb-Esteve, María-Salud eGarcía-Ayllón, Javier eSáez-Valero
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-06-01
Series:Frontiers in Neurology
Subjects:
Cerebrospinal Fluid
Presenilin-1
Alzheimer’s disease
BACE1
TACE
soluble amyloid precursor protein
Online Access:http://journal.frontiersin.org/Journal/10.3389/fneur.2015.00125/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fneur.2015.00125/full

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