Colony-stimulating factor 1 receptor inhibition prevents disruption of the blood-retina barrier during chronic inflammation

Abstract Background Microglia-associated inflammation is closely related to the pathogenesis of various retinal diseases such as uveitis and diabetic retinopathy, which are associated with increased vascular permeability. In this study, we investigated the effect of systemic lipopolysaccharide (LPS)...

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Bibliographic Details
Main Authors: Despina Kokona, Andreas Ebneter, Pascal Escher, Martin S. Zinkernagel
Format: Article
Language:English
Published: BMC 2018-12-01
Series:Journal of Neuroinflammation
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12974-018-1373-4