Synthesis and preclinical evaluation of novel 99mTc-labeled PSMA ligands for radioguided surgery of prostate cancer

Abstract Background Radioguided surgery (RGS) has recently emerged as a valuable new tool in the management of recurrent prostate cancer (PCa). After preoperative injection of a 99mTc-labeled prostate-specific membrane antigen (PSMA) inhibitor, radioguided intraoperative identification and resection...

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Bibliographic Details
Main Authors: Jan-Philip Kunert, Max Müller, Thomas Günther, León Stopper, Nicole Urtz-Urban, Roswitha Beck, Hans-Jürgen Wester
Format: Article
Language:English
Published: SpringerOpen 2023-01-01
Series:EJNMMI Research
Subjects:
Online Access:https://doi.org/10.1186/s13550-022-00942-7