SELENOK-dependent CD36 palmitoylation regulates microglial functions and Aβ phagocytosis

SELENOK-dependent CD36 palmitoylation regulates microglial functions and Aβ phagocytosis

Amyloid-beta (Aβ) is a key factor in the onset and progression of Alzheimer's disease (AD). Selenium (Se) compounds show promise in AD treatment. Here, we revealed that selenoprotein K (SELENOK), a selenoprotein involved in immune regulation and potentially related to AD pathology, plays a crit...

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Bibliographic Details
Main Authors: Pei Ouyang, Zhiyu Cai, Jiaying Peng, Shujing Lin, Xiaochun Chen, Changbin Chen, Ziqi Feng, Lin Wang, Guoli Song, Zhonghao Zhang
Format: Article
Language:English
Published: Elsevier 2024-04-01
Series:Redox Biology
Subjects:
Selenoprotein K
Amyloid-beta
Alzheimer's disease
CD36 palmitoylation
Microglial phagocytosis
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231724000405

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http://www.sciencedirect.com/science/article/pii/S2213231724000405

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