Evidence of Selection against Complex Mitotic-Origin Aneuploidy during Preimplantation Development.
Whole-chromosome imbalances affect over half of early human embryos and are the leading cause of pregnancy loss. While these errors frequently arise in oocyte meiosis, many such whole-chromosome abnormalities affecting cleavage-stage embryos are the result of chromosome missegregation occurring duri...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2015-10-01
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| Series: | PLoS Genetics |
| Online Access: | http://europepmc.org/articles/PMC4619652?pdf=render |