Major Contribution of Caspase-9 to Honokiol-Induced Apoptotic Insults to Human Drug-Resistant Glioblastoma Cells

Major Contribution of Caspase-9 to Honokiol-Induced Apoptotic Insults to Human Drug-Resistant Glioblastoma Cells

Temozolomide (TMZ)-induced chemoresistance to human glioblastomas is a critical challenge now. Our previous studies showed that honokiol, a major bioactive constituent of <i>Magnolia officinalis</i> (Houpo), can kill human glioblastoma cells and suppresses glioblastoma growth. This study...

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Bibliographic Details
Main Authors: Gong-Jhe Wu, Sun-Ta Yang, Ruei-Ming Chen
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:Molecules
Subjects:
drug-resistant glioblastomas
honokiol
caspase-9
apoptotic insults
Online Access:https://www.mdpi.com/1420-3049/25/6/1450

Internet

https://www.mdpi.com/1420-3049/25/6/1450

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