Spectroscopic and molecular docking studies on binding interactions of camptothecin drugs with bovine serum albumin

Spectroscopic and molecular docking studies on binding interactions of camptothecin drugs with bovine serum albumin

Abstract This study investigates the binding interactions between bovine serum albumin (BSA) and camptothecin (CPT) drugs (camptothecin, 10-hydroxycamptothecin, topotecan, and irinotecan) using UV–Vis spectroscopy, fluorescence spectroscopy, three-dimensional fluorescence spectroscopy, and molecular...

Full description

Bibliographic Details
Main Authors: Yuhe Wang, Junfeng Li, Xuanda Li, Bingmiao Gao, Jiao Chen, Yun Song
Format: Article
Language:English
Published: Nature Portfolio 2025-03-01
Series:Scientific Reports
Subjects:
Bovine serum albumin
Camptothecin drugs
Binding interactions
Fluorescence Titration
Molecular Docking
Online Access:https://doi.org/10.1038/s41598-025-92607-3

Internet

https://doi.org/10.1038/s41598-025-92607-3

Similar Items