Direct Targeting of the Raf-MEK-ERK Signaling Cascade Inhibits Neuroblastoma Growth

The Raf-MEK-ERK signaling network has been the subject of intense research due to its role in the development of human cancers, including pediatric neuroblastoma (NB). MEK and ERK are the central components of this signaling pathway and are attractive targets for cancer therapy. Approximately 3–5% o...

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Bibliographic Details
Main Authors: Rameswari Chilamakuri, Saurabh Agarwal
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Current Oncology
Subjects:
Online Access:https://www.mdpi.com/1718-7729/29/9/512