Elevated lymphotoxin-α (TNFβ) is associated with intervertebral disc degeneration

Elevated lymphotoxin-α (TNFβ) is associated with intervertebral disc degeneration

Abstract Background Intervertebral disc degeneration (IVDD) is a primary cause of degenerative disc diseases; however, the mechanisms underlying the degeneration remain unclear. The immunoinflammatory response plays an important role in IVDD progression. The inflammatory cytokine lymphotoxin-α (LTα)...

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Bibliographic Details
Main Authors: Zhu Guo, Chensheng Qiu, Christina Mecca, Yang Zhang, Jiang Bian, Yan Wang, Xiaolin Wu, Tianrui Wang, Weiliang Su, Xianglin Li, Wei Zhang, Bohua Chen, Hongfei Xiang
Format: Article
Language:English
Published: BMC 2021-01-01
Series:BMC Musculoskeletal Disorders
Subjects:
Intervertebral disc degeneration
Lymphotoxin-α
TNFβ
Inflammatory response
Cytokine
Online Access:https://doi.org/10.1186/s12891-020-03934-7

Internet

https://doi.org/10.1186/s12891-020-03934-7

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