A novel nonsense mutation in the MIP gene linked to congenital posterior polar cataracts in a Chinese family.
To detect the causative mutation for congenital posterior polar cataracts in a five-generation Chinese family and further explore the potential pathogenesis of this disease.Coding exons, with flanking sequences of five candidate genes, were screened using direct DNA sequencing. The identified mutati...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2015-01-01
|
| Series: | PLoS ONE |
| Online Access: | http://europepmc.org/articles/PMC4372439?pdf=render |