Cell-recruited microspheres for OA treatment by dual-modulating inflammatory and chondrocyte metabolism

Cell-recruited microspheres for OA treatment by dual-modulating inflammatory and chondrocyte metabolism

Osteoarthritis (OA) is a degenerative disease potentially exacerbated due to inflammation, cartilage degeneration, and increased friction. Both mesenchymal stem cells (MSCs) and pro-inflammatory macrophages play important roles in OA. A promising approach to treating OA is to modify multi-functional...

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Bibliographic Details
Main Authors: Yun Zhou, Xu He, Wen Zhang, Weiguo Zhang, Huan Zhao, Xichao Zhou, Qiaoli Gu, Hao Shen, Huilin Yang, Xingzhi Liu, Lixin Huang, Qin Shi
Format: Article
Language:English
Published: Elsevier 2024-08-01
Series:Materials Today Bio
Subjects:
Osteoarthritis
Hydrogel microspheres
Chondroitin sulfate
RGD
Transforming growth factor-β1
Online Access:http://www.sciencedirect.com/science/article/pii/S2590006424001868

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http://www.sciencedirect.com/science/article/pii/S2590006424001868

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