Anticoagulant Related Nephropathy Only Partially Develops in C57BL/6 Mice: Hematuria Is Not Accompanied by Red Blood Cell Casts in the Kidney

Anticoagulant Related Nephropathy Only Partially Develops in C57BL/6 Mice: Hematuria Is Not Accompanied by Red Blood Cell Casts in the Kidney

Anticoagulant-related nephropathy (ARN) may develop in patients that are on anticoagulation therapy. Rats with 5/6 nephrectomy treated with different anticoagulants showed acute kidney injury (AKI) and red blood cell (RBC) casts in the tubules similar to ARN in humans. The aim of the current study w...

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Bibliographic Details
Main Authors: Ajay K. Medipally, Min Xiao, Shahzeb Qaisar, Anjali A. Satoskar, Iouri Ivanov, Brad Rovin, Sergey V. Brodsky
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Medicine
Subjects:
anticoagulant related nephropathy
acute kidney injury
mouse model
5/6 nephrectomy
anticoagulation
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2020.617786/full

Internet

https://www.frontiersin.org/articles/10.3389/fmed.2020.617786/full

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