A murine model of elastase- and cigarette smoke-induced emphysema

A murine model of elastase- and cigarette smoke-induced emphysema

ABSTRACT Objective: To describe a murine model of emphysema induced by a combination of exposure to cigarette smoke (CS) and instillation of porcine pancreatic elastase (PPE). Methods: A total of 38 C57BL/6 mice were randomly divided into four groups: control (one intranasal instillation of 0.9% s...

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Bibliographic Details
Main Authors: Rubia Rodrigues, Clarice Rosa Olivo, Juliana Dias Lourenço, Alyne Riane, Daniela Aparecida de Brito Cervilha, Juliana Tiyaki Ito, Milton de Arruda Martins, Fernanda Degobbi Tenório Quirino dos Santos Lopes
Format: Article
Language:English
Published: Sociedade Brasileira de Pneumologia e Tisiologia
Series:Jornal Brasileiro de Pneumologia
Subjects:
Tabaco
Modelos animais
Enfisema
Fenômenos fisiológicos respiratórios
Lesão pulmonar
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1806-37132017000200095&lng=en&tlng=en

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